C-reactive protein and cardiovascular disease
نویسندگان
چکیده
منابع مشابه
C-reactive protein and cardiovascular disease.
Paul M Ridker, MD, MPH, and Nader Rifai, PhD, eds 393 pages. St-Laurent, Canada: MediEdition Inc; 2006. $68.99. ISBN 0-9780090-0-2. Few biomarkers of disease have generated as much interest, promise, and debate as C-reactive protein (CRP). CRP, a hepatically derived pentraxin, was discovered in 1930 by Rockefeller University investigators William Tillett and Thomas Francis in patients with pneu...
متن کاملC-reactive protein gene polymorphisms, C-reactive protein blood levels, and cardiovascular disease risk.
C-reactive protein (CRP), a blood marker of inflammation and a hallmark of the acute-phase response, has been shown to be a powerful and specific predictor of cardiovascular event risk in populations of otherwise healthy persons. Here we review what is known about CRP gene polymorphisms, discuss how these might affect the epidemiology of CRP and our understanding of CRP's contribution to cardio...
متن کاملC-reactive protein, fibrinogen, and cardiovascular disease prediction.
BACKGROUND There is debate about the value of assessing levels of C-reactive protein (CRP) and other biomarkers of inflammation for the prediction of first cardiovascular events. METHODS We analyzed data from 52 prospective studies that included 246,669 participants without a history of cardiovascular disease to investigate the value of adding CRP or fibrinogen levels to conventional risk fac...
متن کاملUsing C-reactive protein to assess cardiovascular disease risk.
C-reactive protein (CRP), a marker of inflammation, is directly involved in atherogenesis, and elevated CRP levels (as measured by highly sensitive assays) are associated with increased cardiovascular risk. We welcome the recent joint guidelines on CRP testing from the Centers for Disease Control and Prevention and the American Heart Association; however, whereas the guidelines suggest measurin...
متن کاملC-reactive protein is a mediator of cardiovascular disease.
C-reactive protein is postulated to embody an index that can reflect cardiovascular risk and can be used to independently predict major cardiovascular events and mortality. On the other hand, credible experimental data have become available that demonstrate the abundant presence of C-reactive protein in atherosclerotic lesions and, moreover, identify C-reactive protein as an initiator of severa...
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ژورنال
عنوان ژورنال: Journal of Cardiology
سال: 2016
ISSN: 0914-5087
DOI: 10.1016/j.jjcc.2015.11.001